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A full 15-game slate awaits, and we have 15 moneyline picks throughout the day for you to consider.
We've found solid matchups with good odds and a nice opportunity for you to grow your bankroll.
Find out more in my MLB picks for Saturday, May 16.
MLB moneyline picks for May 16
Matchup
Pick
Blue Jays
vs
Tigers
-108
Royals
vs
Cardinals
-113
Diamondbacks
vs
Rockies
-117
Orioles
vs
Nationals
-113
Phillies
vs
Pirates
+117
Marlins
vs
Rays
+122
Reds
vs
Guardians
+150
Cubs
vs
White Sox
-104
Brewers
vs
Twins
-108
Rangers
vs
Astros
-104
Red Sox
vs
Braves
+117
Yankees
vs
Mets
+108
Padres
vs
Mariners
-133
Dodgers
vs
Angels
-138
Giants
vs
Athletics
-127
Prices courtesy of Polymarket as of 5-15.
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Expert MLB moneyline picks for May-16
Blue Jays vs Tigers: Tigers (-108)
Tigers win probability: 52%
Detroit gets the nod at home, where its relievers have been more reliable than Toronto's over the last two weeks.
This is a coin flip with a home-field tiebreaker, and if this game is close late, the Tigers are the team to back.
Royals vs Cardinals: Cardinals (-113)
Cardinals win probability: 53%
St. Louis is seven games better than Kansas City in the standings and opens this series at home.
Kyle Leahy gets the ball against Noah Cameron, and the Cardinals’ lineup has been productive at Busch Stadium all season.
Diamondbacks vs Rockies: Diamondbacks (-117)
Diamonbacks win probability: 53.9%
Although Arizona's lineup has been ice cold lately, the Rockies are 17-27 and (once again) one of the worst teams in baseball.
Their pitching has been getting shelled all season, and Eduardo Rodriguez gives Arizona a real advantage on the mound.
Phillies vs Pirates: Pirates (+117)
Pirates win probability: 46%
Pittsburgh's lineup has been the hottest in baseball over the last two weeks, and the Pirates own a better record than Philadelphia.
With Bubba Chandler taking the mound at PNC Park, the Buccos get the nod.
Orioles vs Nationals: Nationals (-113)
Nationals win probability: 53%
Washington's lineup has been one of the hottest in the NL over the last two weeks, while Baltimore's offense is among the coldest.
The Nationals' hitting edge is significant enough to back the home team.
Marlins vs Rays: Marlins (+122)
Marlins win probability: 45%
Miami’s bullpen has been genuinely stingy lately, and Sandy Alcantara vs. Nick Martinez sets up a real pitching duel.
The Marlins aren’t getting blown out here, and that’s enough to make them worth a look.
Reds vs Guardians: Reds (+150)
Reds win probability: 40%
Cincinnati's lineup isn't far behind Cleveland's recent production, and Chris Paddack gives the Reds tremendous value at this price.
Rangers vs Astros: Rangers (-104)
Rangers win probability: 51%
Houston is 17-28, and its lineup has been among the least productive in the American League recently. Jacob deGrom starting for Texas against Kai-Wei Teng is the entire argument.
Getting a pitcher of deGrom's caliber at essentially even money against a struggling team is a straightforward play.
Cubs vs White Sox: White Sox (-104)
White Sox win probability: 51%
The White Sox have been one of the hottest offensive teams in baseball over the last two weeks, while the Cubs' lineup has gone quiet.
For the first time in a while, the South Side has life in this Windy City rivalry.
Brewers vs Twins: Brewers (-108)
Brewers win probability: 52%
Milwaukee’s relievers have been among the best in baseball lately, and they now face a Twins team whose biggest weakness is the bullpen.
Despite Minnesota getting Royce Lewis back from the IL, that's not going to prevent them from blowing games in late-inning situations.
Padres vs Mariners: Mariners (-133)
Mariners win probability: 57%
San Diego's lineup has been one of the two coldest offenses in baseball lately.
Logan Gilbert is one of the better pitchers in the AL and gets to face that dormant lineup at home.
The price is steep, but the Mariners are worth the price.
Red Sox vs Braves: Red Sox (+117)
Red Sox win probability: 46%
Boston's bullpen has been one of the best in the sport recently, and rookie starter Payton Tolle has proven to be no slouch either.
The Red Sox are a live underdog with real teeth.
Yankees vs Mets: Mets (+108)
Mets win probability: 47%
The New York Yankees' lineup has been one of the best in baseball lately, but Carlos Rodon has been unreliable, and the Mets' bullpen has been sharper than the Yankees' recently.
With Mendoza reportedly on the hot seat, the stakes of the Stadium Series at Citi Field add even more urgency. The home team at nearly even money is worth backing.
Dodgers vs Angels: Dodgers (-138)
Dodgers win probability: 58%
The Angels possess one of the coldest lineups in baseball over the last two weeks. Meanwhile, the Dodgers have a deeper, more talented roster top to bottom, and their bullpen has been sharp lately.
Take the defending champs to pull away in Anaheim.
Giants vs Athletics: Athletics (-127)
Athletics win probability: 55.7%
San Francisco's bullpen has been the worst in baseball over the last two weeks, and the Giants' lineup hasn't fared much better.
The A’s offense continues to take the league by storm, and Luis Severino should deliver a solid start in this Northern California battle.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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